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System Biology


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Systems biology uses algorithms to measure body system balance in a holistic “real-life” forecast. We measure six Systems key to fertility health.​

Temperature is the core issue for Hot PFP men, who generally feel warmer than most other people, and they also tend to be “on the go” types who find it difficult to relax at the end of the day. Their extra heat is often a reflection of their metabolic rate being higher than average. Being too hot affects how sperm develop, so it’s a significant issue for many men.

Hot PFPs are the opposite of Cold PFPs, who have lower or slower fertility metabolism, and as mammals, we’re all relatively warm, but some of us are warmer than others. Hot PFPs can have extra heat in just a specific part of the body, or it can be a more general condition. Temperatures often vary around the body, especially across the lower back, and it’s worth feeling for temperature differences in your lower abdomen, middle and chest. The human body is designed to function within a narrow temperature range, but body temperatures vary depending on:

  • The heat generated in cells
  • Blood circulation
  • Exposure to heat and cold
  • Sex hormone levels
  • Diet
  • Exercise
  • Drugs
  • Age
  • Times of day
  • Infections and inflammation

Because the lower abdomen is where our reproductive organs are, the temperature here affects fertility the most. The effects of unusual body temperature are the main issues that restrict the fertility of Hot and Cold PFPs, and there are two variations to the imbalance. Knowing which is at play is crucial when trying to increase the odds of conceiving.

Variations of Hot

It’s easiest to explain the different temperature issues using the terms “Full” and “Empty”:

  • “Full” refers to an excess (usually coming from outside) that increases temperature, and examples are meningitis or sunstroke.
  • “Empty” refers to a lack of coolness (always internal) that causes a relative excess of heat, and menopausal flushes from lower sex hormones is a classic example.

“Full Hot”

“Full Hot” is relatively simple to explain, as something from outside the body warms it up. Infections by viruses or bacteria are the usual causes, but burns are another option, and the heat that they bring can directly affect fertility. Sexually transmitted infections such as Chlamydia and Gonorrhoea can generate enough heat to distort and block the glands and tubes around a man’s testes, which reduces the chances of natural pregnancy. Having mumps in adulthood is another example, where the swelling and heat in the testes can make men sterile for life.

However, anything that causes inflammation is heating, and allergies, hyper-sensitivities and autoimmune diseases have heating elements to them and change fertility levels. The signs of Full Hot are usually fairly straightforward and appear relatively quickly, with a hot feeling, an aversion to heat, sometimes redness, and people are often thirsty and irritable. Most forms of Full Heat only last as long as it takes the body to fight off an infection, but the immune-related sensitivities can become chronic.

“Empty Hot”

“Empty Hot” is more subtle, as it develops when the body isn’t cool enough, so it’s usually a gradual, non-specific change in temperature until a point arrives when the extra warmth becomes noticeable. The extra heat tends to show up most at the end of the day or when over-tired. When people lack heat, they feel cold, and if they lack coolness, they’ll feel hot.

Menopausal women often get flushes and night sweats, but a lot of men do too. Changes in sex hormones are one reason for Empty Hot, but other hormone imbalances can trigger them, and there are non-hormonal reasons too. The body can also over-react to a fairly standard stimulus when it’s run-down, which can trigger immune system imbalances and inflammation.

Reducing exposure to triggers and generally cooling the body can make the immune system feel less “threatened” and reactive, with gradual reductions in inflammation and heat. Having a cooler body and a less aggressive immune system can be the most crucial thing for sperm health and male fertility.

Heat is by its nature agitating, and when there’s excess heat, it increases the chances of anxiety and disturbed sleep. Sleep disturbances and stress affect the ANS and hormone balance, with clear impacts on sperm health and male sexual function. Thankfully, these issues can usually be significantly improved when people follow the advice for their PFP and take supplements.

Hot PFP and Male Fertility

Being too hot is a significant problem for men as very few sperm that grow at a normal body temperature can fertilise an egg. This is why sperm grow outside the body as it’s cooler there. These sperm made at higher temperatures have higher DNA fragmentation rates and are less likely to form viable pregnancies.

The challenge for Hot PFP men is to reduce all the factors that are causing inflammation and raising their body temperature. Once the external causes of inflammation are removed, the focus shifts towards improving the balance of their immune and autonomic nervous systems and reducing oxidative stress to improve sperm health and DNA integrity.

Morefertile and Hot PFP Men

Premium morefertile® membership gives you access to:

  1. Your secondary PFP (if you have one) 
  2. A rating for each profile and what the combination means for you
  3. Clear dietary advice and recipes
  4. Lifestyle changes to help fluids
  5. Discounts on supplements
  6. Access to cutting-edge testing

We also outline the best ways for Hot PFPs to adjust their weight and manage stress to improve monthly conception rates. The different profiles have different challenges and needs, which is all part of the PFP discussion, along with personalised ways to improve fertility health, and the tests and treatments most likely to be appropriate for you. The morefertile approach:

  • Is informative and empowering
  • Raises general and fertility health
  • Speeds up natural conception times
  • Improves IVF success rates
  • Increases resilience and lowers stress levels