LUFS treatment is based on differentiations that involve disharmonies of the Ren and Chong Mai, as well as both excess and deficient patterns. Luteinised Unruptured Follicle syndrome involves the dominant follicle developing but failing to rupture after the LH surge and the egg is left trapped in the follicle which then becomes a “simple” or “functional” cyst, which usually lasts for about 6 weeks, and produces sex hormones (progesterone and estrogen) that affect following cycles.
Clomephene citrate (clomid) is commonly prescribed to induce ovulation as it’s a relatively cheap and simple way to raise ovulation rates, however for some women it encourages a sticky cervical mucus that reduces fertility. Clomid also increases the likelihood of LUFS and luteal phase defect (LPD) with increasing use, and a study has shown that many women (who previously had normal cycles) developed LUFS when given clomid alongside intra-uterine insemination (IUI):i
- 25% of them had LUFS in the first cycle
- 56.5% had LUFS in the second cycle
- 58.9% of the women who had a third cycle had LUFS
Of course some women became pregnant, but the reoccurrence rate for the women who had LUFS in the first cycle was:
- 78.6% in the second cycle
- 90% by the third cycle
In Chinese medicine LUFS is considered to be due to either of these four patterns:
i ‘The effects of clomiphene citrate upon ovulation and endocrinology when administered to patients with unexplained infertility’ John M. Randall1 and Allan Templeton Hum. Reprod. (1991) 6 (5): 659-664.
ii Professor Yuning Wu (Director of the Beijing Obstetrics and Gynecology Committee)